Product References
Aryl Hydrocarbon Receptor Activation Ameliorates Acute Respiratory Distress Syndrome through Regulation of Th17 and Th22 Cells in the Lungs.
mBio
Holloman BL,Cannon A,Wilson K,Nagarkatti P,Nagarkatti M
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Neutralization
Tue Apr 25 00:00:00 UTC 2023
ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery.
Cell reports
Jakob MO,Spari D,Sànchez Taltavull D,Salm L,Yilmaz B,Doucet Ladevèze R,Mooser C,Pereyra D,Ouyang Y,Schmidt T,Mattiola I,Starlinger P,Stroka D,Tschan F,Candinas D,Gasteiger G,Klose CSN,Diefenbach A,Gomez de Agüero M,Beldi G
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Mar 28 00:00:00 UTC 2023
Gut microbe-derived milnacipran enhances tolerance to gut ischemia/reperfusion injury.
Cell reports. Medicine
Deng F,Hu JJ,Lin ZB,Sun QS,Min Y,Zhao BC,Huang ZB,Zhang WJ,Huang WK,Liu WF,Li C,Liu KX
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Mar 21 00:00:00 UTC 2023
The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut.
The Journal of experimental medicine
Krzywinska E,Sobecki M,Nagarajan S,Zacharjasz J,Tambuwala MM,Pelletier A,Cummins E,Gotthardt D,Fandrey J,Kerdiles YM,Peyssonnaux C,Taylor CT,Sexl V,Stockmann C
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Mon Feb 07 00:00:00 UTC 2022
Expanded IL-22+ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia.
Immune network
Min HK,Moon J,Lee SY,Lee AR,Lee CR,Lee J,Kwok SK,Cho ML,Park SH
16-7222-82 was used in Inhibition Assays to explore the role of circulating group 3 innate lymphoid cells in axial spondyloarthritis and the impact of dyslipidaemia on its pathogenesis.
Wed Dec 01 00:00:00 UTC 2021
Expanded IL-22+ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia.
Immune network
Min HK,Moon J,Lee SY,Lee AR,Lee CR,Lee J,Kwok SK,Cho ML,Park SH
16-7222-82 was used in Inhibition Assays to explore the role of circulating group 3 innate lymphoid cells in axial spondyloarthritis and the impact of dyslipidaemia on its pathogenesis.
Wed Dec 01 00:00:00 UTC 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Thu Jul 22 00:00:00 UTC 2021
CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression.
Proceedings of the National Academy of Sciences of the United States of America
Crawford MP,Sinha S,Renavikar PS,Borcherding N,Karandikar NJ
16-7222-82 was used in Flow Cytometry to eveal a role for IL-17 cytokines in mediating CD4-intrinsic immune resistance.
Tue Aug 11 00:00:00 UTC 2020
Single-cell multi-omics analysis presents the landscape of peripheral blood T-cell subsets in human chronic prostatitis/chronic pelvic pain syndrome.
Journal of cellular and molecular medicine
Zhang M,Liu Y,Chen J,Chen L,Meng J,Yang C,Yin S,Zhang X,Zhang L,Hao Z,Chen X,Liang C
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease.
Alcoholism, clinical and experimental research
Marrero I,Maricic I,Morgan TR,Stolz AA,Schnabl B,Liu ZX,Tsukamoto H,Kumar V
16-7222-82 was used in Flow Cytometry to investigate the role of innate-like unconventional T cells in alcohol-related liver disease.
Fri May 01 00:00:00 UTC 2020
Chlamydia muridarum Alleviates Colitis via the IL-22/Occludin Signal Pathway.
BioMed research international
Wang X,Zeng HC,Huang YR,He QZ
16-7222 was used in Functional assays to suggest that C. muridarum ameliorates ulcerative colitis induced by DSS via the IL-22/occludin signal pathway.
Mon May 24 00:00:00 UTC 2021
Chlamydia muridarum Alleviates Colitis via the IL-22/Occludin Signal Pathway.
BioMed research international
Wang X,Zeng HC,Huang YR,He QZ
16-7222 was used in Functional assays to suggest that C. muridarum ameliorates ulcerative colitis induced by DSS via the IL-22/occludin signal pathway.
Mon May 24 00:00:00 UTC 2021
A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice.
Cellular and molecular gastroenterology and hepatology
Zhang A,Sodhi CP,Wang M,Shores DR,Fulton W,Prindle T,Brosten S,O'Hare E,Lau A,Ding H,Jia H,Lu P,White JR,Hui J,Sears CL,Hackam DJ,Alaish SM
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Fri Jul 09 00:00:00 UTC 2021
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
JCI insight
Busbee PB,Menzel L,Alrafas HR,Dopkins N,Becker W,Miranda K,Tang C,Chatterjee S,Singh U,Nagarkatti M,Nagarkatti PS
16-7222-82 was used in Neutralization and Functional assays to suggest that I3C attenuates colitis primarily through induction of IL-22, which leads to modulation of gut microbiota that promote antiinflammatory butyrate.
Thu Jan 16 00:00:00 UTC 2020
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
JCI insight
Busbee PB,Menzel L,Alrafas HR,Dopkins N,Becker W,Miranda K,Tang C,Chatterjee S,Singh U,Nagarkatti M,Nagarkatti PS
16-7222-82 was used in Neutralization and Functional assays to suggest that I3C attenuates colitis primarily through induction of IL-22, which leads to modulation of gut microbiota that promote antiinflammatory butyrate.
Thu Jan 16 00:00:00 UTC 2020
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.
Nature communications
Napier RJ,Lee EJ,Davey MP,Vance EE,Furtado JM,Snow PE,Samson KA,Lashley SJ,Brown BR,Horai R,Mattapallil MJ,Xu B,Callegan MC,Uebelhoer LS,Lancioni CL,Vehe RK,Binstadt BA,Smith JR,Caspi RR,Rosenzweig HL
16-7222-82 was used in Flow Cytometry to reveal a non-conventional, T cell-intrinsic function for Nod2 in suppression of Th17 immunity and experimental uveitis.
Mon Oct 26 00:00:00 UTC 2020
The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells.
Immunity
Omenetti S,Bussi C,Metidji A,Iseppon A,Lee S,Tolaini M,Li Y,Kelly G,Chakravarty P,Shoaie S,Gutierrez MG,Stockinger B
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Jul 16 00:00:00 UTC 2019
Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells.
Gastroenterology
Cook L,Stahl M,Han X,Nazli A,MacDonald KN,Wong MQ,Tsai K,Dizzell S,Jacobson K,Bressler B,Kaushic C,Vallance BA,Steiner TS,Levings MK
16-7222-82 was used in Flow cytometry/Cell sorting to develop methods to isolate and expand human type 1 Treg cells and define their functions.
Sun Dec 01 00:00:00 UTC 2019
Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis.
Mucosal immunology
Mathur R,Alam MM,Zhao XF,Liao Y,Shen J,Morgan S,Huang T,Lee H,Lee E,Huang Y,Zhu X
16-7222-82 was used in Sample Preparation to determine that mTOR inhibitor rapamycin or mTOR deletion in CX3Cr1+ mononuclear phagocytes inhibits expression of interleukin (IL)-23, accompanied by reduced intestinal production of IL-22 and ameliorated fibrosis in the TNBS-induced fibrosis mouse model.
Wed May 01 00:00:00 UTC 2019
CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis.
European journal of immunology
Affandi AJ,Silva-Cardoso SC,Garcia S,Leijten EFA,van Kempen TS,Marut W,van Roon JAG,Radstake TRDJ
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Thu Mar 01 00:00:00 UTC 2018
Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Kamdar K,Johnson AMF,Chac D,Myers K,Kulur V,Truevillian K,DePaolo RW
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in ELISA
Sun Jul 01 00:00:00 UTC 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Thu Sep 26 00:00:00 UTC 2019
Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo.
Scientific reports
Parigi SM,Czarnewski P,Das S,Steeg C,Brockmann L,Fernandez-Gaitero S,Yman V,Forkel M,Höög C,Mjösberg J,Westerberg L,Färnert A,Huber S,Jacobs T,Villablanca EJ
16-7222 was used in Flow cytometry/Cell sorting to indicate that Flt3L expands CHILPs in the bone marrow, which might be associated with specific inflammatory conditions.
Tue Jan 09 00:00:00 UTC 2018
WASH maintains NKp46+ ILC3 cells by promoting AHR expression.
Nature communications
Xia P,Liu J,Wang S,Ye B,Du Y,Xiong Z,Han ZG,Tong L,Fan Z
16-7222 was used in Flow cytometry/Cell sorting to study how WASH-mediated AHR expression has a critical function in the maintenance of NKp46(+) ILC3s.
Wed Jun 07 00:00:00 UTC 2017
CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis.
Nature immunology
Cibrian D,Saiz ML,de la Fuente H,Sánchez-Díaz R,Moreno-Gonzalo O,Jorge I,Ferrarini A,Vázquez J,Punzón C,Fresno M,Vicente-Manzanares M,Daudén E,Fernández-Salguero PM,Martín P,Sánchez-Madrid F
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease.
JCI insight
Li W,Liu L,Gomez A,Zhang J,Ramadan A,Zhang Q,Choi SW,Zhang P,Greenson JK,Liu C,Jiang D,Virts E,Kelich SL,Chu HW,Flynn R,Blazar BR,Hanenberg H,Hanash S,Paczesny S
16-7222 was used in Flow cytometry/Cell sorting to discover an ICOS-stimulated, Th17-prone CD4(+)CD146(+)CCR5(+) T cell subset that may serve as an early gastrointestinal graft-versus-host-disease biomarker.
Thu May 05 00:00:00 UTC 2016
A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice.
Nature communications
Tripathi D,Venkatasubramanian S,Cheekatla SS,Paidipally P,Welch E,Tvinnereim AR,Vankayalapati R
16-7222 was used in Flow cytometry/Cell sorting to investigate the role of NK1.1(+) cells in islet allograft tolerance in a model of type 1 diabetes, showing that a TLR9 agonist promotes IL-22-dependent allograft survival.
Fri Dec 16 00:00:00 UTC 2016
Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production.
Arthritis research & therapy
Pinto LG,Talbot J,Peres RS,Franca RF,Ferreira SH,Ryffel B,Aves-Filho JC,Figueiredo F,Cunha TM,Cunha FQ
16-7222 was used in in vivo experiments to investigate the role of IL-22 in the early phase of antigen-induced arthritis in mice.
Wed Sep 02 00:00:00 UTC 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Sep 29 00:00:00 UTC 2015
Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.
Proceedings of the National Academy of Sciences of the United States of America
Yeaman MR,Filler SG,Chaili S,Barr K,Wang H,Kupferwasser D,Hennessey JP,Fu Y,Schmidt CS,Edwards JE,Xiong YQ,Ibrahim AS
16-7222 was used in Neutralization experiments to evaluate the efficacy and immunologic mechanisms of a vaccine containing a recombinant glycoprotein antigen in mouse skin and skin structure infection.
Tue Dec 23 00:00:00 UTC 2014
Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.
Proceedings of the National Academy of Sciences of the United States of America
Yeaman MR,Filler SG,Chaili S,Barr K,Wang H,Kupferwasser D,Hennessey JP,Fu Y,Schmidt CS,Edwards JE,Xiong YQ,Ibrahim AS
16-7222 was used in Neutralization experiments to evaluate the efficacy and immunologic mechanisms of a vaccine containing a recombinant glycoprotein antigen in mouse skin and skin structure infection.
Tue Dec 23 00:00:00 UTC 2014
Commensal bacteria protect against food allergen sensitization.
Proceedings of the National Academy of Sciences of the United States of America
Stefka AT,Feehley T,Tripathi P,Qiu J,McCoy K,Mazmanian SK,Tjota MY,Seo GY,Cao S,Theriault BR,Antonopoulos DA,Zhou L,Chang EB,Fu YX,Nagler CR
16-7222 was used in Functional assays to examine the connection between the commensal microbiome and sensitisation to food allergens.
Tue Sep 09 00:00:00 UTC 2014
Interleukin-22 promotes T helper 1 (Th1)/Th17 immunity in chlamydial lung infection.
Molecular medicine (Cambridge, Mass.)
Peng Y,Gao X,Yang J,Shekhar S,Wang S,Fan Y,Zhao W,Yang X
16-7222 was used in Blocking experiments to investigate the production and function of IL-22 in host defence against chlamydial lung infection.
Thu Mar 20 00:00:00 UTC 2014
Interleukin-22 promotes T helper 1 (Th1)/Th17 immunity in chlamydial lung infection.
Molecular medicine (Cambridge, Mass.)
Peng Y,Gao X,Yang J,Shekhar S,Wang S,Fan Y,Zhao W,Yang X
16-7222 was used in Blocking experiments to investigate the production and function of IL-22 in host defence against chlamydial lung infection.
Thu Mar 20 00:00:00 UTC 2014
Interleukin-22 promotes T helper 1 (Th1)/Th17 immunity in chlamydial lung infection.
Molecular medicine (Cambridge, Mass.)
Peng Y,Gao X,Yang J,Shekhar S,Wang S,Fan Y,Zhao W,Yang X
16-7222 was used in Blocking experiments to investigate the production and function of IL-22 in host defence against chlamydial lung infection.
Thu Mar 20 00:00:00 UTC 2014
Interleukin-22 promotes T helper 1 (Th1)/Th17 immunity in chlamydial lung infection.
Molecular medicine (Cambridge, Mass.)
Peng Y,Gao X,Yang J,Shekhar S,Wang S,Fan Y,Zhao W,Yang X
16-7222 was used in Blocking experiments to investigate the production and function of IL-22 in host defence against chlamydial lung infection.
Thu Mar 20 00:00:00 UTC 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using IL-22 monoclonal antibody (Product # 16-7222-82) in Flow Cytometry
Tue Jul 01 00:00:00 UTC 2014
The secretion of IL-22 from mucosal NKp44⁺ NK cells is associated with microbial translocation and virus infection in SIV/SHIV-infected Chinese macaques.
Journal of immunology research
Wang W,Wu F,Cong Z,Liu K,Qin C,Wei Q
16-7222 was used in Flow cytometry/Cell sorting to investigate the role of a novel subtype of innate lymphoid cells, the NKp44(+) NK cells, in SIV-induced microbial translocation.
Tue Dec 01 00:00:00 UTC 2015
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation.
The Journal of experimental medicine
Mielke LA,Jones SA,Raverdeau M,Higgs R,Stefanska A,Groom JR,Misiak A,Dungan LS,Sutton CE,Streubel G,Bracken AP,Mills KH
16-7222 was used in in vitro experiments to provide novel insights into the molecular events controlling IL-22 transcription.
Mon Jun 03 00:00:00 UTC 2013
Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease.
Clinical immunology (Orlando, Fla.)
Xu H,Feely SL,Wang X,Liu DX,Borda JT,Dufour J,Li W,Aye PP,Doxiadis GG,Khosla C,Veazey RS,Sestak K
16-7222 was used in Flow cytometry/Cell sorting to indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
Mon Apr 01 00:00:00 UTC 2013
Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques.
Journal of immunology (Baltimore, Md. : 1950)
Canary LA,Vinton CL,Morcock DR,Pierce JB,Estes JD,Brenchley JM,Klatt NR
16-7222 was used in Flow cytometry/Cell sorting to determine whether pre-existing GI-associated mucosal damage affects the progression of AIDS following HIV infection.
Fri Mar 15 00:00:00 UTC 2013
