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Invitrogen
IL-34 Polyclonal Antibody
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Product Details
PA5-20585
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 16 amino acid peptide from near the amino terminus of human IL-34.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11155576
Product Specific Information
Despite its predicted molecular weight, IL-34 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is human brain tissue lysate.
PA5-20585 can be used with blocking peptide PEP-0705.
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IL-34; ILN; Interleukin; Interleukin-34; Interleukin34
Gene Aliases: 2010004A03Rik; AI593503; C16orf77; IL-34; IL34
UniProt ID: (Human) Q6ZMJ4, (Mouse) Q8R1R4, (Rat) Q4KM46
Entrez Gene ID: (Human) 146433, (Mouse) 76527, (Rat) 498951
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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