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IL13RA2 Polyclonal Antibody

IL13RA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IL13RA2 Antibody (11059-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 11059-1-AP ( IL13RA2 antibody at dilution of 1:200 (under 40x lens).

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Product Details

11059-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 4 publications 4 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

IL13RA2 Fusion Protein Ag1534 (24-330 aa encoded by BC020739)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SSSDTEIKV NPPQDFEIVD PGYLGYLYLQ WQPPLSLDHF KECTVEYELK YRNIGSETWK TIITKNLHYK DGFDLNKGIE AKIHTLLPWQ CTNGSEVQSS WAETTYWISP QGIPETKVQD MDCVYYNWQY LLCSWKPGIG VLLDTNYNLF YWYEGLDHAL QCVDYIKADG QNIGCRFPYL EASDYKDFYI CVNGSSENKP IRSSYFTFQL QNIVKPLPPV YLTFTRESSC EIKLKWSIPL GPIPARCFDY EIEIREDDTT LVTATVENET YTLKTTNETR QLCFVVRSKV NIYCSDDGIW SEWSDKQC (24-330 aa encoded by BC020739 )

Target Information

IL13RA2 (interleukin-13 receptor subunit alpha-2) is closely related to IL13RA1, a subuint of the interleukin 13 receptor complex. This protein binds as a monomer to IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury.

Frontiers in pharmacology

Liu J,Li Z,Lao Y,Jin X,Wang Y,Jiang B,He R,Yang S

Fri Feb 24 00:00:00 UTC 2023

Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models.

Cancer reports (Hoboken, N.J.)

Nagai T,Terada N,Fujii M,Nagata Y,Nakahara K,Mukai S,Okasho K,Kamiyama Y,Akamatsu S,Kobayashi T,Iida K,Denawa M,Hagiwara M,Inoue T,Ogawa O,Kamoto T

Wed Feb 01 00:00:00 UTC 2023

In situ targeting nanoparticles-hydrogel hybrid system for combined chemo-immunotherapy of glioma.

Journal of controlled release : official journal of the Controlled Release Society

Wang X,Ye L,He W,Teng C,Sun S,Lu H,Li S,Lv L,Cao X,Yin H,Lv W,Xin H

Sun May 01 00:00:00 UTC 2022

IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.

Cancer biology & medicine

Feng T,Wang J,Cheng K,Lu Q,Zhao R,Wang S,Zhang Q,Ge L,Pan J,Song G,Wang L

Mon Oct 18 00:00:00 UTC 2021

IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.

Cancer biology & medicine

Feng T,Wang J,Cheng K,Lu Q,Zhao R,Wang S,Zhang Q,Ge L,Pan J,Song G,Wang L

Mon Oct 18 00:00:00 UTC 2021

IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.

Cancer biology & medicine

Feng T,Wang J,Cheng K,Lu Q,Zhao R,Wang S,Zhang Q,Ge L,Pan J,Song G,Wang L

Mon Oct 18 00:00:00 UTC 2021

Titanium nanoparticles potentially affect gingival tissue through IL-13α2 receptor expression.

Journal of oral science

Ishikawa T,Sugawara S,Kihara H,Hanasaka T,Hatakeyama W,Sasaki M,Kondo H

Tue Jun 29 00:00:00 UTC 2021

Resveratrol and its Nanoparticle suppress Doxorubicin/Docetaxel-resistant anaplastic Thyroid Cancer Cells in vitro and in vivo.

Nanotheranostics

Xiong L,Lin XM,Nie JH,Ye HS,Liu J

Tue Jun 01 00:00:00 UTC 2021

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE^-/- Mice.

Frontiers in physiology

Xue Q,Chen L,Yu J,Sun K,Ye L,Zheng J

Fri Aug 06 00:00:00 UTC 2021

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE^-/- Mice.

Frontiers in physiology

Xue Q,Chen L,Yu J,Sun K,Ye L,Zheng J

Fri Aug 06 00:00:00 UTC 2021

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE^-/- Mice.

Frontiers in physiology

Xue Q,Chen L,Yu J,Sun K,Ye L,Zheng J

Fri Aug 06 00:00:00 UTC 2021

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE^-/- Mice.

Frontiers in physiology

Xue Q,Chen L,Yu J,Sun K,Ye L,Zheng J

Fri Aug 06 00:00:00 UTC 2021

Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.

Frontiers in pharmacology

Du Y,Jia C,Liu Y,Li Y,Wang J,Sun K

Fri Feb 12 00:00:00 UTC 2021

IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.

Biochemical and biophysical research communications

Zhang Y,Li C,Zhang M,Li Z

Tue Sep 18 00:00:00 UTC 2018

IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.

Biochemical and biophysical research communications

Zhang Y,Li C,Zhang M,Li Z

Tue Sep 18 00:00:00 UTC 2018

IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.

Biochemical and biophysical research communications

Zhang Y,Li C,Zhang M,Li Z

Tue Sep 18 00:00:00 UTC 2018

IL-13 and IL-13Rα1 are overexpressed in extranodal natural killer/T cell lymphoma and mediate tumor cell proliferation.

Biochemical and biophysical research communications

Zhang Y,Li C,Zhang M,Li Z

Tue Sep 18 00:00:00 UTC 2018

Outer brain barriers in rat and human development.

Frontiers in neuroscience

Brøchner CB,Holst CB,Møllgård K

Wed Apr 08 00:00:00 UTC 2015

Outer brain barriers in rat and human development.

Frontiers in neuroscience

Brøchner CB,Holst CB,Møllgård K

Wed Apr 08 00:00:00 UTC 2015

Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.

Oncology reports

Akiyama Y,Komiyama M,Miyata H,Yagoto M,Ashizawa T,Iizuka A,Oshita C,Kume A,Nogami M,Ito I,Watanabe R,Sugino T,Mitsuya K,Hayashi N,Nakasu Y,Yamaguchi K

Tue Apr 01 00:00:00 UTC 2014

Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.

Oncology reports

Akiyama Y,Komiyama M,Miyata H,Yagoto M,Ashizawa T,Iizuka A,Oshita C,Kume A,Nogami M,Ito I,Watanabe R,Sugino T,Mitsuya K,Hayashi N,Nakasu Y,Yamaguchi K

Tue Apr 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: cancer/testis antigen 19; CD213a2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; interleukin 13 binding protein; interleukin 13 receptor alpha 2 chain; interleukin 13 receptor, alpha 2; Interleukin-13 receptor subunit alpha-2; Interleukin-13-binding protein

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Gene Aliases: CD213A2; CT19; IL-13R; IL-13R-alpha-2; IL13BP; IL13R; IL13RA2

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UniProt ID: (Human) Q14627, (Mouse) O88786

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Entrez Gene ID: (Human) 3598, (Mouse) 16165, (Rat) 171060

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Function(s)

signal transducer activity cytokine receptor activity

Process(es)

negative regulation of immunoglobulin production immunoglobulin mediated immune response cytokine-mediated signaling pathway negative regulation of mast cell degranulation cellular response to mechanical stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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IL13RA2 Polyclonal Antibody

IL13RA2 Antibody (11059-1-AP) in IHC (P)

Product Details

11059-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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