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Proteintech
IL2RG Polyclonal Antibody
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Product Details
11409-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IL2RG Fusion Protein Ag1911 (1-369 aa encoded by BC014972)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLKPSLPFT SLLFLQLPLL GVGLNTTILT PNGNEDTTAD FFLTTMPTDS LSVSTLPLPE VQCFVFNVEY MNCTWNSSSE PQPTNLTLHY WYKNSDNDKV QKCSHYLFSE EITSGCQLQK KEIHLYQTFV VQLQDPREPR RQATQMLKLQ NLVIPWAPEN LTLHKLSESQ LELNWNNRFL NHCLEHLVQY RTDWDHSWTE QSVDYRHKFS LPSVDGQKRY TFRVRSRFNP LCGSAQHWSE WSHPIHWGSN TSKENPFLFA LEAVVISVGS MGLIISLLCV YFWLERTMPR IPTLKNLEDL VTEYHGNFSA WSGVSKGLAE SLQPDYSERL CLVSEIPPKG GALGEGPGAS PCNQHSPYWA PPCYTLKPET (1-369 aa encoded by BC014972)
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2R gamma; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; p64
Gene Aliases: [g]c; Ab2-183; CD132; CIDX; gamma(c); gc; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785, (Mouse) P34902
Entrez Gene ID: (Human) 3561, (Rat) 140924, (Mouse) 16186
immune response
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
positive regulation of T cell differentiation in thymus
positive regulation of B cell differentiation
positive regulation of lymphocyte differentiation
MAPK cascade
signal transduction
viral process
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
positive regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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