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Invitrogen
ING2 Recombinant Rabbit Monoclonal Antibody (2H44L53)
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FIGURE: 1 / 5
ING2 Antibody (702744) in WB
Western blot analysis was performed on Whole cell extracts (30 µg lysate) of HCT 116 (Lane 1), Caco-2 (Lane 2), COLO 205 (Lane 3), HT-29 (Lane 4), U-2 OS (Lane 5), MCF-7 (Lane 6) and tissue extracts of Mouse Colon (Lane7). The blots were probed with Anti-ING2 Recombinant Rabbit Monoclonal Antibody (Product # 702744, 1:200 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 32 kDa band corresponding to ING2 was ... View More
Product Details
702744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
2H44L53
Immunogen
Protein corresponding to human ING2 [aa1-aa280]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2724520
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ING1Lp; Inhibitor of growth 1-like protein; inhibitor of growth family, member 2; Inhibitor of growth protein 2; p32; p33ING2
Gene Aliases: 2810011M06Rik; ING1L; ING2; Ing2b; P33ING2
UniProt ID: (Human) Q9H160, (Mouse) Q9ESK4
Entrez Gene ID: (Human) 3622, (Mouse) 69260
transcription, DNA-templated
regulation of transcription, DNA-templated
male meiosis I
spermatogenesis
spermatid development
negative regulation of cell proliferation
chromatin modification
sperm motility
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of growth
positive regulation of apoptotic process
positive regulation of transcription, DNA-templated
male germ-line stem cell asymmetric division
seminiferous tubule development
negative regulation of apoptotic signaling pathway
signal transduction
covalent chromatin modification
positive regulation of histone deacetylation
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of cellular senescence
regulation of response to DNA damage stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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