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Immunogen sequence: EHFTALGSF YFLHESLKNI YQFDFKAKKY RKVAGKEIYS DTLESTPMLE KEKFPQDYFP ECKWSRKGFI RTRWCIADCA FDLVNIHLFH DASNLVAWET SPSVYSGIRH KALGYVLDRI IDQRFEKVSY FVFGDFNFRL DSKSVVETLC TKATMQTVRA ADTNEVVKLI FRESDNDRKV MLQLEKKLFD YFNQEVFRDN NGTALLEFDK ELSVFKDRLY ELDISFPPSY PYSEDARQGE QYMNTRCPAW CDRILMSPSA KELVLRSESE EKVVTYDHIG PNVCMGDHKP VFLAFRIMPG AGKPHAHVHK CCVVQ (99-412 aa encoded by B C096280)
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 43 kDa inositol polyphosphate 5-phophatase; 43 kDa inositol polyphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; Inositol polyphosphate-5-phosphatase A; inositol polyphosphate-5-phosphatase, 40kD; inositol polyphosphate-5-phosphatase, 40kDa; inositol trisphosphate-5-phosphatase, 40kD; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol 1,4,5-trisphosphate 5-phosphatase; type I inositol-1,4,5-trisphosphate 5-phophatase; type I inositol-1,4,5-trisphosphate 5-phosphatase
Gene Aliases: 5PTASE; INPP5A
UniProt ID: (Human) Q14642, (Rat) D3ZZX1, (Mouse) Q7TNC9
Entrez Gene ID: (Human) 3632, (Rat) 365382, (Mouse) 212111
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