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Invitrogen
INPP5F Monoclonal Antibody (OTI1D4)
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INPP5F Antibody (MA5-27229) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human pancreas tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a INPP5F monoclonal antibody (Product # MA5-27229) at a dilution of 1:500.
Product Details
MA5-27229
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1D4
Immunogen
Full length human recombinant protein of INPP5F produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723292
Target Information
SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.3.36; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
Gene Aliases: hSAC2; INPP5F; KIAA0966; MSTP007; MSTP047; MSTPO47; SAC2
UniProt ID: (Human) Q9Y2H2
Entrez Gene ID: (Human) 22876
positive regulation of receptor recycling
phosphatidylinositol biosynthetic process
cardiac muscle hypertrophy in response to stress
phosphatidylinositol catabolic process
negative regulation of tyrosine phosphorylation of Stat3 protein
phosphatidylinositol dephosphorylation
phosphatidylinositol-mediated signaling
negative regulation of axon regeneration
regulation of protein kinase B signaling
clathrin-mediated endocytosis
regulation of cell motility
regulation of endocytic recycling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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