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          • Primary Antibodies ›
          • INTS1 Antibodies

          Bethyl Laboratories

          INT1 Polyclonal Antibody

          View all (5) INTS1 antibodies

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          Cite INT1 Polyclonal Antibody

          • Antibody Testing Data (2)
          INT1 Antibody in Western Blot (WB)
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          INT1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          INT1 Antibody (A300-361A) in WB

          Detection of human and mouse INT1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-INT1 antibody (Product # A300-361A) (lot A300-361A-2) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          INT1 Antibody in Western Blot (WB)
          INT1 Antibody in Immunoprecipitation (IP)

          Product Details

          A300-361A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:2,500
          -

          Immunoprecipitation (IP)

          2-5 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residues 150 and 200 of human integrator complex subunit 1.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          phosphate/tris citrate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Target Information

          INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Int1; Integrator complex subunit 1

          View more View less

          Gene Aliases: 1110015K06Rik; INT1; INTS1; KIAA1440; NET28; UNQ1821/PRO3434

          View more View less

          UniProt ID: (Human) Q8N201, (Mouse) Q6P4S8

          View more View less

          Entrez Gene ID: (Human) 26173, (Mouse) 68510

          View more View less

          Function(s)
          molecular_function
          Process(es)
          blastocyst growth inner cell mass cell proliferation snRNA processing U2 snRNA 3'-end processing negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process snRNA transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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