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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CPSF3L Antibodies

          Bethyl Laboratories

          INT11 Polyclonal Antibody

          View all (11) CPSF3L antibodies
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          Datasheet
          Protocols
          Questions & Answers

          Cite INT11 Polyclonal Antibody

          • Antibody Testing Data (3)
          INT11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          INT11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          INT11 Antibody (A301-274A) in IHC (P)

          Detection of human INT11 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-INT11 (Product # A301-274A) (Lot 4) used at a dilution of 1:5,000 (0.2 µg/mL). Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          INT11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          INT11 Antibody in Western Blot (WB)
          INT11 Antibody in Immunoprecipitation (IP)

          Product Details

          A301-274A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000 to 1:5,000
          -

          Immunoprecipitation (IP)

          2-10 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 550 and 600 of human integrator complex subunit 11.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          tris citrate/phosphate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

          Based on 100% sequence identity, this antibody is predicted to react with Orangutan

          Target Information

          Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Int11; Integrator complex subunit 11; Protein related to CPSF subunits of 68 kDa; RC-68; related to CPSF subunits 68 kDa

          View more View less

          Gene Aliases: 2410006F12Rik; AU044035; CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68

          View more View less

          UniProt ID: (Human) Q5TA45, (Mouse) Q9CWS4

          View more View less

          Entrez Gene ID: (Human) 54973, (Mouse) 71957

          View more View less

          Function(s)
          protein binding hydrolase activity molecular_function
          Process(es)
          snRNA processing snRNA transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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