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Proteintech
IQSEC2 Polyclonal Antibody
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Product Details
25321-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IQSEC2 Fusion Protein Ag18226 (189-386 aa encoded by BC156683)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FEEYEKAQN PAYFEGKPAS LDEGAMAGAR SHRLERGLPY GGSCGGGIDG GGSSVTTSGE FSNDITELED SFSKQVKSLA ESIDEALNCH PSGPMSEEPG SAQLEKRESK EQQEDSSATS FSDLPLYLDD TVPQQSPERL PSTEPPPQGR PEFWAPAPLP PVPPPVPSGT REDGSREEGT RRGPGCLECR DFRLRAAHL (189-386 aa encoded by BC156683)
Target Information
This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brefeldin A resistant Arf-guanine nucleotide exchange factor 1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1b; brefeldin A resistant Arf-guanine nucleotide exchange factor 1c; IQ motif and SEC7 domain-containing protein 2
Gene Aliases: BRAG1; IQSEC2; KIAA0522; MRX1; MRX78
UniProt ID: (Human) Q5JU85
Entrez Gene ID: (Human) 23096
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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