Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
IRF6 Antibody (MA5-42964) in ICC/IF
Immunocytochemistry analysis of IRF6 in HeLa cells. Samples were treated with 4% PFA, permeabilized with 1% Triton X-100 in PBS, and blocked with 10% serum, incubated in IRF6 monoclonal antibody (Product # MA5-42964) at a dilution of 1:60, followed by Alexa Fluor 488-conjugated Goat Anti-mouse IgG.
Product Details
MA5-42964
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG3
Class
Monoclonal
Type
Antibody
Clone
06
Immunogen
A synthetic peptide corresponding to the C-terminus of the human IRF6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912105
Product Specific Information
Specificity: Human IRF6
Target Information
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Interferon regulatory factor 6; IRF-6
Gene Aliases: IRF6; LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) O14896
Entrez Gene ID: (Human) 3664
transcription, DNA-templated
cell cycle arrest
negative regulation of cell proliferation
keratinocyte differentiation
keratinocyte proliferation
positive regulation of transcription, DNA-templated
cell development
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
mammary gland epithelial cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support