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Invitrogen
ISCU Polyclonal Antibody
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Product Details
PA5-30470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ISCU. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.66 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547944
Product Specific Information
Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, ISCU-transfected 293T.
Predicted reactivity: Mouse (97%), Rat (97%), Drosophila (84%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Iron-sulfur cluster assembly enzyme ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial; IscU iron-sulfur cluster scaffold homolog; ISCU2; NifU-like N-terminal domain containing; NifU-like N-terminal domain-containing protein; NifU-like protein
Gene Aliases: 2310020H20Rik; AA407971; HML; hnifU; ISCU; ISU2; NIFU; NIFUN
UniProt ID: (Human) Q9H1K1, (Mouse) Q9D7P6
Entrez Gene ID: (Human) 23479, (Mouse) 66383
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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