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Invitrogen
ITGA3 Polyclonal Antibody, PE
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Product Details
PA5-46895
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant mouse Integrin alpha 3/CD49c Phe33-Glu993
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
Buffered saline solution with BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607345
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Integrin alpha 2, rmIntegrin alpha 4, rmIntegrin alpha 5, rmIntegrin alpha E, rmIntegrin alpha M, rmIntegrin alpha V and rmIntegrin alpha X is observed.
Target Information
ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha3 integrin; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; Galactoprotein B3; GAPB3; Integrin alpha-3; Integrin alpha3; VLA-3 subunit alpha
Gene Aliases: AA407068; CD49C; GAPB3; Itga3
UniProt ID: (Mouse) Q62470
Entrez Gene ID: (Mouse) 16400
Performance Guarantee
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