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Invitrogen
ITGA5/ITGB1 Recombinant Rabbit Monoclonal Antibody (008)
Product Details
MA5-30937
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
008
Immunogen
Recombinant Human ITGA5 & ITGB1 Heterodimer protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2786606
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human ITGA5 & ITGB1 Heterodimer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD29; CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; Fibronectin receptor subunit beta; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; Glycoprotein IIa; GPIIA; integrin alpha 5; Integrin alpha-5; Integrin alpha-F; integrin beta 1; Integrin beta-1; Integrin beta1; integrin VLA-4 beta subunit; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); very late activation protein 5, alpha subunit; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLA-5
Gene Aliases: CD29; CD49e; FNRA; FNRB; GPIIA; ITGA5; ITGB1; MDF2; MSK12; VLA-5; VLA-BETA; VLA5A; VLAB
UniProt ID: (Human) P08648, (Human) P05556
Entrez Gene ID: (Human) 3678, (Human) 3688
virus receptor activity
epidermal growth factor receptor binding
platelet-derived growth factor receptor binding
integrin binding
protein binding
vascular endothelial growth factor receptor 2 binding
metal ion binding
glycoprotein binding
fibronectin binding
protease binding
actin binding
coreceptor activity
protein kinase binding
protein domain specific binding
C-X3-C chemokine binding
protein complex binding
peptide binding
laminin binding
protein heterodimerization activity
cell adhesion molecule binding
alpha-actinin binding
collagen binding involved in cell-matrix adhesion
cadherin binding involved in cell-cell adhesion
G1/S transition of mitotic cell cycle
in utero embryonic development
cell fate specification
tissue homeostasis
cell migration involved in sprouting angiogenesis
cellular calcium ion homeostasis
cellular defense response
homophilic cell adhesion via plasma membrane adhesion molecules
leukocyte cell-cell adhesion
cell-matrix adhesion
calcium-independent cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
visual learning
regulation of collagen catabolic process
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
cell migration
formation of radial glial scaffolds
B cell differentiation
extracellular matrix organization
positive regulation of cell migration
negative regulation of cell projection organization
cell-substrate adhesion
receptor internalization
protein transport within lipid bilayer
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
response to gonadotropin
negative regulation of Rho protein signal transduction
response to drug
positive regulation of apoptotic process
stress fiber assembly
positive regulation of MAPK cascade
positive regulation of GTPase activity
sarcomere organization
negative regulation of neuron differentiation
positive regulation of endocytosis
viral entry into host cell
mesodermal cell differentiation
axon extension
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
leukocyte migration
leukocyte tethering or rolling
regulation of cell cycle
cardiac muscle cell differentiation
maternal process involved in female pregnancy
bicellular tight junction assembly
cellular response to mechanical stimulus
cellular response to vitamin D
cellular response to low-density lipoprotein particle stimulus
cellular response to ionizing radiation
positive regulation of establishment of protein localization to plasma membrane
negative regulation of anoikis
angiogenesis
cell-substrate junction assembly
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
memory
positive regulation of vascular endothelial growth factor receptor signaling pathway
wound healing, spreading of epidermal cells
endodermal cell differentiation
positive regulation of sprouting angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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