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Product Details
H00008516-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
2G7
Immunogen
ITGA8 (NP_003629, 836 a.a. approximately 935 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: SDTILEVGWP FSARDEFLLY IFHIQTLGPL QCQPNPNINP QDIKPAASPE DTPELSAFLR NSTIPHLVRK RDVHVVEFHR QSPAKILNCT NIECLQISCA
Target Information
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: integrin alpha 8; Integrin alpha-8; integrin, alpha 8
Gene Aliases: ITGA8
UniProt ID: (Human) P53708
Entrez Gene ID: (Human) 8516
metanephros development
kidney development
cell-matrix adhesion
integrin-mediated signaling pathway
brain development
memory
single organismal cell-cell adhesion
cell projection organization
extracellular matrix organization
positive regulation of transforming growth factor beta receptor signaling pathway
substrate adhesion-dependent cell spreading
inner ear morphogenesis
establishment of protein localization
mesodermal cell differentiation
smooth muscle tissue development
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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