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ITGB6 (Integrin alpha-V/beta-6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalization of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
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Protein Aliases: integrin beta 6; Integrin beta-6; integrin, beta 6
Gene Aliases: AI1H; ITGB6
UniProt ID: (Human) P18564
Entrez Gene ID: (Human) 3694
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