Proteintech

ITLN1 Polyclonal Antibody

ITLN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ITLN1 Antibody (11770-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human small intestine using 11770-1-AP (ITLN1 antibody) at dilution of 1:50 (under 40x lens).

ITLN1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11770-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 6 publications 6 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ITLN1 Fusion Protein Ag2424 (1-313 aa encoded by BC020664)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNQLSFLLF LIATTRGWST DEANTYFKEW TCSSSPSLPR SCKEIKDECP SAFDGLYFLR TENGVIYQTF CDMTSGGGGW TLVASVHEND MRGKCTVGDR WSSQQGSKAV YPEGDGNWAN YNTFGSAEAA TSDDYKNPGY YDIQAKDLGI WHVPNKSPMQ HWRNSSLLRY RTDTGFLQTL GHNLFGIYQK YPVKYGEGKC WTDNGPVIPV VYDFGDAQKT ASYYSPYGQR EFTAGFVQFR VFNNERAANA LCAGMRVTGC NTEHHCIGGG GYFPEASPQQ CGDFSGFDWS GYGTHVGYSS SREITEAAVL LFYR (1-313 aa encoded by BC020664)

Target Information

ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Mucociliary Wnt signaling promotes cilia biogenesis and beating.

Nature communications

Seidl C,Da Silva F,Zhang K,Wohlgemuth K,Omran H,Niehrs C

Mon Mar 06 00:00:00 UTC 2023

Intelectin1 ameliorates macrophage activation via inhibiting the nuclear factor kappa B pathway.

Endocrine journal

Kobayashi H,Uchimura K,Ishii T,Takahashi K,Mori K,Tsuchiya K,Furuya F

Mon May 30 00:00:00 UTC 2022

Intelectin1 ameliorates macrophage activation via inhibiting the nuclear factor kappa B pathway.

Endocrine journal

Kobayashi H,Uchimura K,Ishii T,Takahashi K,Mori K,Tsuchiya K,Furuya F

Mon May 30 00:00:00 UTC 2022

Molecular properties and ligand specificity of zebrafish intelectin-2.

Fish & shellfish immunology

Singrang N,Sitthiyotha T,Chomanee N,Watthanasak C,Chunsrivirot S,Wangkanont K

Fri Apr 01 00:00:00 UTC 2022

Biochemical and ligand binding properties of recombinant Xenopus laevis cortical granule lectin-1.

Heliyon

Deetanya P,Sitthiyotha T,Chomanee N,Chunsrivirot S,Wangkanont K

Mon Aug 01 00:00:00 UTC 2022

Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.

Frontiers in cell and developmental biology

Niu X,Cheng Y,Zhang M,Du L,Wu X,Lu C,Li X,Liu S,Zhao A,Zhang S,Wu Z,Ding B,Shi W,Wang C,Yang Y,Tian Y

Wed Feb 16 00:00:00 UTC 2022

Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.

Frontiers in cell and developmental biology

Niu X,Cheng Y,Zhang M,Du L,Wu X,Lu C,Li X,Liu S,Zhao A,Zhang S,Wu Z,Ding B,Shi W,Wang C,Yang Y,Tian Y

Wed Feb 16 00:00:00 UTC 2022

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.

The Journal of experimental medicine

Wang Y,Song W,Wang J,Wang T,Xiong X,Qi Z,Fu W,Yang X,Chen YG

Mon Feb 03 00:00:00 UTC 2020

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.

The Journal of experimental medicine

Wang Y,Song W,Wang J,Wang T,Xiong X,Qi Z,Fu W,Yang X,Chen YG

Mon Feb 03 00:00:00 UTC 2020

Autocrine action of adipokine omentin-1 in the SW480 colon cancer cell line.

Oncology letters

Zhang Y,Zhao X,Chen M

Wed Jan 01 00:00:00 UTC 2020

Autocrine action of adipokine omentin-1 in the SW480 colon cancer cell line.

Oncology letters

Zhang Y,Zhao X,Chen M

Wed Jan 01 00:00:00 UTC 2020

Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates.

Nature communications

Kim HY,Jackson TR,Stuckenholz C,Davidson LA

Fri Jan 31 00:00:00 UTC 2020

Omentin-1 attenuates adipose tissue inflammation via restoration of TXNIP/NLRP3 signaling in high-fat diet-induced obese mice.

Fundamental & clinical pharmacology

Zhou H,Zhang Z,Qian G,Zhou J

Tue Dec 01 00:00:00 UTC 2020

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.

Mucosal immunology

Yi L,Cheng D,Zhang K,Huo X,Mo Y,Shi H,Di H,Zou Y,Zhang H,Zhao J,Xu Y,Erle DJ,Zhen G

Wed Nov 01 00:00:00 UTC 2017

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.

Mucosal immunology

Yi L,Cheng D,Zhang K,Huo X,Mo Y,Shi H,Di H,Zou Y,Zhang H,Zhao J,Xu Y,Erle DJ,Zhen G

Wed Nov 01 00:00:00 UTC 2017

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.

Mucosal immunology

Yi L,Cheng D,Zhang K,Huo X,Mo Y,Shi H,Di H,Zou Y,Zhang H,Zhao J,Xu Y,Erle DJ,Zhen G

Wed Nov 01 00:00:00 UTC 2017

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.

Mucosal immunology

Yi L,Cheng D,Zhang K,Huo X,Mo Y,Shi H,Di H,Zou Y,Zhang H,Zhao J,Xu Y,Erle DJ,Zhen G

Wed Nov 01 00:00:00 UTC 2017

Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.

The Journal of biological chemistry

Wangkanont K,Wesener DA,Vidani JA,Kiessling LL,Forest KT

Fri Mar 11 00:00:00 UTC 2016

Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.

The Journal of biological chemistry

Wangkanont K,Wesener DA,Vidani JA,Kiessling LL,Forest KT

Fri Mar 11 00:00:00 UTC 2016

Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.

Journal of proteomics

Kim HJ,Kang UB,Lee H,Jung JH,Lee ST,Yu MH,Kim H,Lee C

Wed Jun 06 00:00:00 UTC 2012

Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.

Journal of proteomics

Kim HJ,Kang UB,Lee H,Jung JH,Lee ST,Yu MH,Kim H,Lee C

Wed Jun 06 00:00:00 UTC 2012

Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.

Journal of proteomics

Kim HJ,Kang UB,Lee H,Jung JH,Lee ST,Yu MH,Kim H,Lee C

Wed Jun 06 00:00:00 UTC 2012

Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes.

Journal of proteomics

Kim HJ,Kang UB,Lee H,Jung JH,Lee ST,Yu MH,Kim H,Lee C

Wed Jun 06 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: calcium-dependent galactosyl-specific lectin; Endothelial lectin HL-1; FLJ20022; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding); intelectin 1 (galactofuranose binding)-like; intelectin 2; intelectin 5; intelectin a; Intelectin-1; Intelectin-1a; Intestinal lactoferrin receptor; ITLN-1; Omentin

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Gene Aliases: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; Itln1a; Itln2; Itln5; Itlna; LFR; omentin; UNQ640/PRO1270

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UniProt ID: (Human) Q8WWA0, (Mouse) Q5IWS3

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Entrez Gene ID: (Human) 55600, (Rat) 498284, (Mouse) 16429

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Function(s)

carbohydrate binding

Process(es)

positive regulation of protein phosphorylation response to nematode positive regulation of glucose import

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ITLN1 Polyclonal Antibody

ITLN1 Antibody (11770-1-AP) in IHC (P)

Product Details

11770-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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