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ITLN1 Antibody (PA5-96614) in IHC (P)
Immunohistochemistry analysis of ITLN1 in paraffin-embedded mouse intestine. Samples were incubated with ITLN1 Polyclonal antibody (Product # PA5-96614) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-96614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-313 of human ITLN1 (NP_0600952)
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808416
Product Specific Information
Immunogen sequence: TDEANTYFKE WTCSSSPSLP RSCKEIKDEC PSAFDGLYFL RTENGVIYQT FCDMTSGGGG WTLVASVHEN DMRGKCTVGD RWSSQQGSKA VYPEGDGNWA NYNTFGSAEA ATSDDYKNPG YYDIQAKDLG IWHVPNKSPM QHWRNSSLLR YRTDTGFLQT LGHNLFGIYQ KYPVKYGEGK CWTDNGPVIP VVYDFGDAQK TASYYSPYGQ REFTAGFVQF RVFNNERAAN ALCAGMRVTG CNTEHHCIGG GGYFPEASPQ QCGDFSGFDW SGYGTHVGYS SSREITEAAV LLFYR; Positive Samples: Mouse heart, Rat intestine; Cellular Location: Cell membrane, GPI-anchor, Lipid-anchor
Target Information
ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium-dependent galactosyl-specific lectin; FLJ20022; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding)-like; intelectin 2; intelectin 5; intelectin a; intelectin-1; Intelectin-1a; Intestinal lactoferrin receptor
Gene Aliases: IntL; Itln; Itln1; Itln1a; Itln2; Itln5; Itlna; Lfr
UniProt ID: (Mouse) Q5IWS3
Entrez Gene ID: (Rat) 498284, (Mouse) 16429
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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