Proteintech

ITM2A Polyclonal Antibody

ITM2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

ITM2A Antibody (18306-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver using 18306-1-AP (ITM2A antibody) at dilution of 1:50 (under 40x lens).

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Product Details

18306-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

This gene encodes a type II membrane protein that belongs to the ITM2 family. Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx^-/- mice.

Bone research

Lin J,Yang Y,Zhou W,Dai C,Chen X,Xie Y,Han S,Liu H,Hu Y,Tang C,Bunpetch V,Zhang D,Chen Y,Zou X,Chen D,Liu W,Ouyang H

Fri Jan 07 00:00:00 UTC 2022

The regenerating skeletal muscle niche drives satellite cell return to quiescence.

iScience

Cutler AA,Pawlikowski B,Wheeler JR,Dalla Betta N,Elston T,O'Rourke R,Jones K,Olwin BB

Fri Jun 17 00:00:00 UTC 2022

Exploring ITM2A as a new potential target for brain delivery.

Fluids and barriers of the CNS

Cegarra C,Chaves C,Déon C,Do TM,Dumas B,Frenzel A,Kuhn P,Roudieres V,Guillemot JC,Lesuisse D

Mon Mar 21 00:00:00 UTC 2022

Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.

Cell communication and signaling : CCS

Zhou C,Wang M,Yang J,Xiong H,Wang Y,Tang J

Thu Aug 22 00:00:00 UTC 2019

Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.

Cell communication and signaling : CCS

Zhou C,Wang M,Yang J,Xiong H,Wang Y,Tang J

Thu Aug 22 00:00:00 UTC 2019

Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.

Cell communication and signaling : CCS

Zhou C,Wang M,Yang J,Xiong H,Wang Y,Tang J

Thu Aug 22 00:00:00 UTC 2019

Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells.

PloS one

Kihara M,Kiyoshima T,Nagata K,Wada H,Fujiwara H,Hasegawa K,Someya H,Takahashi I,Sakai H

Fri Nov 13 00:00:00 UTC 2015

Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells.

PloS one

Kihara M,Kiyoshima T,Nagata K,Wada H,Fujiwara H,Hasegawa K,Someya H,Takahashi I,Sakai H

Fri Nov 13 00:00:00 UTC 2015

Identification of early gene expression changes during human Th17 cell differentiation.

Blood

Tuomela S,Salo V,Tripathi SK,Chen Z,Laurila K,Gupta B,Äijö T,Oikari L,Stockinger B,Lähdesmäki H,Lahesmaa R

Thu Jun 07 00:00:00 UTC 2012

Identification of early gene expression changes during human Th17 cell differentiation.

Blood

Tuomela S,Salo V,Tripathi SK,Chen Z,Laurila K,Gupta B,Äijö T,Oikari L,Stockinger B,Lähdesmäki H,Lahesmaa R

Thu Jun 07 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: BRICHOS domain containing 2A; Integral membrane protein 2A; Protein E25

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Gene Aliases: AW108051; BRICD2A; E25; E25A; Itm2; ITM2A; UNQ603/PRO1189

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UniProt ID: (Human) O43736, (Mouse) Q61500

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Entrez Gene ID: (Human) 9452, (Rat) 317218, (Mouse) 16431

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Function(s)

beta-amyloid binding protein binding

Process(es)

nervous system development negative regulation of amyloid precursor protein biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ITM2A Polyclonal Antibody

ITM2A Antibody (18306-1-AP) in IHC (P)

Product Details

18306-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

Bioinformatics

Performance Guarantee

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