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Invitrogen
ITPA Polyclonal Antibody
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FIGURE: 1 / 6
ITPA Antibody (PA5-102393) in ICC/IF
Immunofluorescent analysis of ITPA in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and ITPA polyclonal antibody (Product # PA5-102393) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-102393
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ITPA(Accession Q9BY32), corresponding to amino acid residues R130-R180.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851798
Product Specific Information
Antibody detects endogenous levels of total ITPA.
Target Information
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inosine triphosphatase (nucleoside triphosphate pyrophosphatase); inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; inosine triphosphate pyrophosphohydrolase; ITPase; ITPase {ECO:0000255|HAMAP-Rule:MF_03148}; My049 protein; Non-canonical purine NTP pyrophosphatase; non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Non-standard purine NTP pyrophosphatase; non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; NTPase; NTPase {ECO:0000255|HAMAP-Rule:MF_03148}; nucleoside triphosphate pyrophosphatase; Nucleoside-triphosphate diphosphatase; nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Nucleoside-triphosphate pyrophosphatase; nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Putative oncogene protein hlc14-06-p
Gene Aliases: 2010016I08Rik; AU020102; C20orf37; dJ794I6.3; HLC14-06-P; Itp; ITPA; ITPase; My049; NTPase; OK/SW-cl.9
UniProt ID: (Human) Q9BY32, (Rat) D3ZW55, (Mouse) Q9D892
Entrez Gene ID: (Human) 3704, (Rat) 311422, (Mouse) 16434
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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