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Immunogen sequence: MQTFLKGKR VGYWLSEKKI KKLNFQAFAE LCRKRGMEVV QLNLSRPIEE QGPLDVIIHK LTDVILEADQ NDSQSLELVH RFQEYIDAHP ETIVLDPLPA IRTLLDRSKS YELIRKIEAY MEDDRICSPP FMELTSLCGD DTMRLLEKNG LTFPFICKTR VAHGTNSHEM AIVFNQEGLN AIQPPCVVQN FINHNAVLYK VFVVGESYTV VQRPSLKNFS AGTSDRESIF FNSHNVSKPE SSSVLTELDK IEGVFERPSD EVIRELSRAL RQALGVSLFG IDIIINNQTG QHAVIDINAF PGDCQVCFIE GWKTD (1-314 aa encoded by BC007428)
ITPK1 encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-tetrakisphosphate 1-kinase; Inositol-triphosphate 5/6-kinase; ins(1,3,4)P(3) 5/6-kinase
Gene Aliases: BC031182; ITPK1; ITRPK1
UniProt ID: (Human) Q13572, (Mouse) Q8BYN3
Entrez Gene ID: (Human) 3705, (Mouse) 217837
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