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Invitrogen
ITPK1 Monoclonal Antibody (OTI1F5)
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ITPK1 Antibody (MA5-27033) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min. Following antigen retrieval, tissues were probed with a ITPK1 monoclonal antibody (Product # MA5-27033) at a dilution of 1:150.
Product Details
MA5-27033
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1F5
Immunogen
Human recombinant protein fragment corresponding to amino acids 309-391 of ITPK1 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2724535
Target Information
ITPK1 encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-tetrakisphosphate 1-kinase; Inositol-triphosphate 5/6-kinase; ins(1,3,4)P(3) 5/6-kinase
Gene Aliases: ITPK1; ITRPK1
UniProt ID: (Human) Q13572
Entrez Gene ID: (Human) 3705
magnesium ion binding
catalytic activity
ATP binding
isomerase activity
inositol tetrakisphosphate 1-kinase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
inositol-1,3,4-trisphosphate 6-kinase activity
inositol-1,3,4-trisphosphate 5-kinase activity
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
inositol-3,4,6-trisphosphate 1-kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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