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Invitrogen
ITPKA Polyclonal Antibody
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ITPKA Antibody (PA5-85786) in IHC (F)
Immunohistochemistry (Frozen) analysis of ITPKA was performed in frozen-sectioned adult mouse cerebellum tissue using ITPKA Polyclonal Antibody (Product # PA5-85786) at a dilution of 1:250 (Green). Red: NF-H, stained by NF-H antibody diluted at 1:500. Blue: Fluoroshield with DAPI. Antigen Retrieval: Citrate buffer, pH 6.0, 10 min.
Product Details
PA5-85786
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse IP3KA. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.78 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792922
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (100%).
Positive Control: mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.7.1.127; inositol 1,4,5-triphosphate 3-kinase; Inositol 1,4,5-trisphosphate 3-kinase A; inositol 145-triphosphate 3-kinase; Inositol-trisphosphate 3-kinase A; insP 3-kinase A; IP3 3 kinase A; IP3 3-kinase A; IP3-kinase A; IP3K A
Gene Aliases: Itpka
UniProt ID: (Mouse) Q8R071, (Rat) P17105
Entrez Gene ID: (Mouse) 228550, (Rat) 81677
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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