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Invitrogen
ITSN2 Polyclonal Antibody
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Product Details
PA5-95786
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 500-620 of human ITSN2 (NP_0062682)
Conjugate
Form
Liquid
Concentration
1.76 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807588
Product Specific Information
Immunogen sequence: GKHQQISGRL QDVRLKKQTQ KTELEVLDKQ CDLEIMEIKQ LQQELQEYQN KLIYLVPEKQ LLNERIKNMQ FSNTPDSGVS LLHKKSLEKE ELCQRLKEQL DALEKETASK LSEMDSFNNQ L; Positive Samples: U-87MG, LO2, Jurkat, HeLa; Cellular Location: Cytoplasm
Target Information
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EH and SH3 domains protein 2; EH domain and SH3 domain regulator of endocytosis 2; Eh domain, SH3 domain regulator of endocytosis 2; intersectin 2; Intersectin-2; SH3 domain protein 1B; SH3 domain-containing protein 1B; SH3P18; SH3P18-like WASP-associated protein
Gene Aliases: AI327390; Ese2; ITSN2; KIAA1256; mKIAA1256; PRO2015; SH3D1B; SH3P18; SWA; SWAP
UniProt ID: (Human) Q9NZM3
Entrez Gene ID: (Human) 50618, (Rat) 313934, (Mouse) 20403
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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