Proteintech

IVD Polyclonal Antibody

IVD Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 13

IVD Antibody (10822-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed MCF-7 cells using 10822-1-AP (IVD antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

IVD Antibody in Immunohistochemistry (Paraffin) (IHC (P))

IVD Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10822-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Plant, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

IVD Fusion Protein Ag1252 (1-423 aa encoded by BC017202)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MATATRLLG CRVASWRLRP PLAGFVSQRA HSLLPVDDAI NGLSEEQRQL RQTMAKFLQE HLAPKAQEID RSNEFKNLRE FWKQLGNLGV LGITAPVQYG GSGLGYLEHV LVMEEISRAS GAVGLSYGAH SNLCINQLVR NGNEAQKEKY LPKLISGEYI GALAMSEPNA GSDVVSMKLK AEKKGNHYIL NGNKFWITNG PDADVLIVYA KTDLAAVPAS RGITAFIVEK GMPGFSTSKK LDKLGMRGSN TCELIFEDCK IPAANILGHE NKGVYVLMSG LDLERLVLAG GPLGLMQAVL DHTIPYLHVR EAFGQKIGHF QLMQGKMADM YTRLMACRQY VYNVAKACDE GHCTAKDCAG VILYSAECAT QVALDGIQCF GGNGYINDFP MGRFLRDAKL YEIGAGTSEV RRLVIGRAFN ADFH (1-423 aa encoded by BC017202)

Target Information

Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis.

Journal of translational medicine

Peng C,Zhang Y,Lang X,Zhang Y

Wed Feb 01 00:00:00 UTC 2023

Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis.

Journal of translational medicine

Peng C,Zhang Y,Lang X,Zhang Y

Wed Feb 01 00:00:00 UTC 2023

Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.

Cellular and molecular life sciences : CMLS

Peng MZ,Shao YX,Li XZ,Zhang KD,Cai YN,Lin YT,Jiang MY,Liu ZC,Su XY,Zhang W,Jiang XL,Liu L

Tue Jun 21 00:00:00 UTC 2022

The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures.

Plant cell reports

Brito DS,Quinhones CGS,Neri-Silva R,Heinemann B,Schertl P,Cavalcanti JHF,Eubel H,Hildebrandt T,Nunes-Nesi A,Braun HP,Araújo WL

Tue Feb 01 00:00:00 UTC 2022

Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration.

Proteomics. Clinical applications

Stauch KL,Villeneuve LM,Purnell PR,Ottemann BM,Emanuel K,Fox HS

Thu Dec 01 00:00:00 UTC 2016

Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration.

Proteomics. Clinical applications

Stauch KL,Villeneuve LM,Purnell PR,Ottemann BM,Emanuel K,Fox HS

Thu Dec 01 00:00:00 UTC 2016

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.

Molecular endocrinology (Baltimore, Md.)

Horn S,Kirkegaard JS,Hoelper S,Seymour PA,Rescan C,Nielsen JH,Madsen OD,Jensen JN,Krüger M,Grønborg M,Ahnfelt-Rønne J

Fri Jan 01 00:00:00 UTC 2016

Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.

Molecular endocrinology (Baltimore, Md.)

Horn S,Kirkegaard JS,Hoelper S,Seymour PA,Rescan C,Nielsen JH,Madsen OD,Jensen JN,Krüger M,Grønborg M,Ahnfelt-Rønne J

Fri Jan 01 00:00:00 UTC 2016

Broad connections in the Arabidopsis seed metabolic network revealed by metabolite profiling of an amino acid catabolism mutant.

The Plant journal : for cell and molecular biology

Gu L,Jones AD,Last RL

Mon Feb 01 00:00:00 UTC 2010

Broad connections in the Arabidopsis seed metabolic network revealed by metabolite profiling of an amino acid catabolism mutant.

The Plant journal : for cell and molecular biology

Gu L,Jones AD,Last RL

Mon Feb 01 00:00:00 UTC 2010

Proteomic analysis of stargazer mutant mouse neuronal proteins involved in absence seizure.

Journal of neurochemistry

Ryu MJ,Lee C,Kim J,Shin HS,Yu MH

Sat Mar 01 00:00:00 UTC 2008

Proteomic analysis of stargazer mutant mouse neuronal proteins involved in absence seizure.

Journal of neurochemistry

Ryu MJ,Lee C,Kim J,Shin HS,Yu MH

Sat Mar 01 00:00:00 UTC 2008

Bioinformatics

Protein Aliases: Butyryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; isovaleryl dehydrogenase; Isovaleryl-CoA dehydrogenase, mitochondrial; IVD

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Gene Aliases: 1300016K07Rik; 6720455E18Rik; ACAD2; AI463340; IVD

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UniProt ID: (Human) P26440, (Rat) P12007, (Mouse) Q9JHI5

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Entrez Gene ID: (Human) 3712, (Rat) 24513, (Mouse) 56357

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Function(s)

fatty-acyl-CoA binding isovaleryl-CoA dehydrogenase activity electron carrier activity flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor acyl-CoA dehydrogenase activity oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors

Process(es)

leucine metabolic process leucine catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase protein homooligomerization branched-chain amino acid catabolic process lipid homeostasis metabolic process oxidation-reduction process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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IVD Polyclonal Antibody

IVD Antibody (10822-1-AP) in ICC/IF

Product Details

10822-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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