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Invitrogen
Ifabotuzumab Humanized Recombinant Human Monoclonal Antibody
FIGURE: 1 / 1
Ifabotuzumab Humanized Antibody (MA5-42078) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human EPHA3/REK4 protein expressed in CHO cells using a Ifabotuzumab biosimilar monoclonal antibody (Product # MA5-42078). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Product Details
MA5-42078
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human EPHA3/REK4
Conjugate
Form
Liquid
Concentration
1.07 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.5
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911221
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Ifabotuzumab is a biosimilar that targets EPHA3. EPHA3 (EPA receptor A3), also known as ETK, HEK, ETK1, HEK4, TYRO4, is belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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