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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Integrin alpha 3/beta 1 Antibodies

          Bioss

          Integrin Alpha 3 + Beta 1 Polyclonal Antibody

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          Datasheet
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          Datasheet
          Protocols
          Questions & Answers

          Cite Integrin Alpha 3 + Beta 1 Polyclonal Antibody

          • Antibody Testing Data (4)
          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
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          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          Integrin Alpha 3 + Beta 1 Antibody (BS-1057R) in ICC/IF

          Image provided by One World Lab validation program. MCF-7 cells probed with Rabbit Anti-Integrin Alpha 3 + Beta 1 Polyclonal Antibody (bs-1057R) at 1:50 for 60 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Alexa Fluor 488 Conjugated secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Integrin Alpha 3 + Beta 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Integrin Alpha 3 + Beta 1 Antibody in Western Blot (WB)

          Product Details

          BS-1057R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50
          -

          Flow Cytometry (Flow)

          1:20-1:100
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Mixed KLH conjugated synthetic peptide derived from human Integrin Alpha 3 (976-1025/1051) + Beta 1 (35-47/798).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha3beta1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; Beta OL; Beta oligodendroglia; CD29; CD49 antigen-like family member C; CD49c; Fibronectin receptor subunit beta; FRP-2; Galactoprotein B3; GAPB3; Glycoprotein IIa; GPIIA; integrin alpha 3; Integrin alpha-3; integrin beta 1; integrin beta 1 (fibronectin receptor beta); Integrin beta-1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); testicular tissue protein Li 96; testicular tissue protein Li 98; very late activation protein 3 receptor, alpha-3 subunit; very late activation protein, beta polypeptide; VLA-3 subunit alpha; VLA-4 subunit beta

          View more View less

          Gene Aliases: 4633401G24Rik; AA407068; AA409975; AA960159; CD29; CD49C; ENSMUSG00000051907; FNRB; FRP-2; GAP-B3; GAPB3; Gm9863; GPIIA; ILNEB; ITGA3; ITGB1; MDF2; MSK12; MSK18; VCA-2; VL3A; VLA-BETA; VLA3a; VLAB

          View more View less

          UniProt ID: (Human) P26006, (Human) P05556, (Mouse) Q62470, (Mouse) Q3TWH6, (Rat) P49134

          View more View less

          Entrez Gene ID: (Human) 3675, (Human) 3688, (Rat) 360606, (Mouse) 16400, (Mouse) 16412, (Rat) 24511

          View more View less

          Function(s)
          glycoprotein binding fibronectin binding protease binding integrin binding protein binding collagen binding protein domain specific binding laminin binding metal ion binding protein heterodimerization activity virus receptor activity actin binding coreceptor activity protein kinase binding C-X3-C chemokine binding protein complex binding peptide binding cell adhesion molecule binding alpha-actinin binding collagen binding involved in cell-matrix adhesion cadherin binding involved in cell-cell adhesion receptor activity receptor binding kinase binding
          Process(es)
          neuron migration cell-matrix adhesion integrin-mediated signaling pathway heart development memory positive regulation of gene expression positive regulation of epithelial cell migration positive regulation of cell-substrate adhesion positive regulation of neuron projection development regulation of transforming growth factor beta receptor signaling pathway regulation of Wnt signaling pathway extracellular matrix organization lung development regulation of BMP signaling pathway negative regulation of cell projection organization response to gonadotropin negative regulation of Rho protein signal transduction exploration behavior response to drug skin development mesodermal cell differentiation leukocyte migration maternal process involved in female pregnancy nephron development positive regulation of establishment of protein localization to plasma membrane dendritic spine maintenance renal filtration G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification tissue homeostasis cell migration involved in sprouting angiogenesis cellular calcium ion homeostasis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation negative regulation of cell proliferation germ cell migration visual learning regulation of collagen catabolic process response to activity cell migration formation of radial glial scaffolds B cell differentiation positive regulation of cell migration cell-substrate adhesion receptor internalization protein transport within lipid bilayer cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion positive regulation of apoptotic process stress fiber assembly positive regulation of MAPK cascade positive regulation of GTPase activity sarcomere organization negative regulation of neuron differentiation positive regulation of endocytosis viral entry into host cell axon extension dendrite morphogenesis positive regulation of peptidyl-tyrosine phosphorylation regulation of immune response leukocyte tethering or rolling regulation of cell cycle cardiac muscle cell differentiation bicellular tight junction assembly cellular response to mechanical stimulus cellular response to vitamin D cellular response to low-density lipoprotein particle stimulus cellular response to ionizing radiation negative regulation of anoikis cell adhesion fusion of sperm to egg plasma membrane single-organism behavior neuron projection development negative regulation of cell differentiation positive regulation of neuron differentiation cardiac muscle tissue development response to nutrient levels response to transforming growth factor beta
          It has to be done as per old AB suggested Products section.
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