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Search Thermo Fisher Scientific
Immunogen sequence: MDLSASMDD DLNTIKELGS RLSKEMSKLT SNFRLGFGSF VEKPVSPFVK TTPEEIANPC SSIPYFCLPT FGFKHILPLT NDAERFNEIV KNQKISANID TPEGGFDAIM QAAVCKEKIG WRNDSLHLLV FVSDADSHFG MDSKLAGIVI PNDGLCHLDS KNEYSMSTVL EYPTIGQLID KLVQNNVLLI FAVTQEQVHL YENYAKLIPG ATVGLLQKDS GNILQLIISA YEELRSEVEL EVLGDTEGLN LSFTAICNNG TLFQHQKKCS HMKVGDTASF SVTVNIPHCE RRSRHII (139-434 aa encoded by BC121178 )
ITGB6 (Integrin alpha-V/beta-6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalization of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: integrin beta 6; Integrin beta-6; integrin, beta 6
Gene Aliases: 2210409C20Rik; 4831415H04Rik; AI1H; ITGB6
UniProt ID: (Human) P18564, (Rat) Q6AYF4, (Mouse) Q9Z0T9
Entrez Gene ID: (Human) 3694, (Rat) 311061, (Mouse) 16420
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