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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • J Chain Antibodies

          Invitrogen

          J Chain Polyclonal Antibody

          Advanced Verification
          1 Published Figure
          1 Reference
          View all (31) J Chain antibodies

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          Datasheet
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          Datasheet
          Protocols
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          Cite J Chain Polyclonal Antibody

          • Antibody Testing Data (4)
          • Published Figures (1)
          • Advanced Verification (1)
          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          J Chain Antibody (PA5-83707) in IHC (P)

          Immunohistochemical analysis of J Chain in human duodenum using J Chain Polyclonal Antibody (Product # PA5-83707) shows strong cytoplasmic positivity in lymphoid cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          J Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          J Chain Antibody in Western Blot (WB)
          J Chain Antibody

          Product Details

          PA5-83707

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human JCHAIN. Recombinant protein control fragment (Product #RP-102957).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.08 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790860

          Product Specific Information

          Immunogen sequence: VDNKCKCARI TSRIIRSSED PNEDIVERNI RIIVPLNNRE NISDPTSPLR TRFVYHLSDL CKKCDPTEVE LDNQIVTATQ SNICDEDSAT ETCYTYDRNK CYTAVVPLVY GGETKMVETA

          Target Information

          J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: IgJ chain; Immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; J chain; Joining chain of multimeric IgA and IgM

          View more View less

          Gene Aliases: IGCJ; IGJ; JCH; JCHAIN

          View more View less

          UniProt ID: (Human) P01591

          View more View less

          Entrez Gene ID: (Human) 3512

          View more View less

          Function(s)
          single-stranded DNA binding antigen binding IgA binding phosphatidylcholine binding immunoglobulin receptor binding protein homodimerization activity peptidoglycan binding
          Process(es)
          retina homeostasis adaptive immune response glomerular filtration receptor-mediated endocytosis immune response antibacterial humoral response positive regulation of protein oligomerization innate immune response positive regulation of respiratory burst
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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