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Invitrogen
JAM2 Polyclonal Antibody
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JAM2 Antibody (PA5-30788) in WB
Western blot analysis of JAM2 was performed by separating 30 µg of human tissue extract by 12% SDS-PAGE. Proteins were transferred to a membrane and probed with a JAM2 Polyclonal Antibody (Product # PA5-30788) at a dilution of 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-30788
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human JAM-B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548262
Product Specific Information
Recommended positive controls: THP-1.
Predicted reactivity: Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AU016127; CD322; JAM-2; JAM-B; JAM-IT/VE-JAM; Junctional adhesion molecule 2; Junctional adhesion molecule B; RP23-253E17.2; Vascular endothelial junction-associated molecule; VE-JAM
Gene Aliases: C21orf43; CD322; JAM-B; JAM2; JAMB; PRO245; UNQ219/PRO245; VE-JAM; VEJAM
UniProt ID: (Human) P57087
Entrez Gene ID: (Human) 58494
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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