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Abnova
JAM3 Polyclonal Antibody, MaxPab™
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Product Details
H00083700-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
JAM3 (AAH12147.1, 1 a.a. approximately 310 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MALRRPPRLR LCARLPDFFL LLLFRGCLIG AVNLKSSNRT PVVQEFESVE LSCIITDSQT SDPRIEWKKI QDEQTTYVFF DNKIQGDLAG RAEILGKTSL KIWNVTRRDS ALYRCEVVAR NDRKEIDEIV IELTVQVKPV TPVCRVPKAV PVGKMATLHC QESEGHPRPH YSWYRNDVPL PTDSRANPRF RNSSFHLNSE TGTLVFTAVH KDDSGQYYCI ASNDAGSARC EEQEMEVYDL NIGGIIGGVL VVLAVLALIT LGICCAYRRG YFINNKQDGE SYKNPGKPDG VNYIRTDEEG DFRHKSSFVI
Target Information
JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JAM-2; JAM-3; JAM-C; junction cell adhesion molecule 3; junction cell adhesion molecule C; Junctional adhesion molecule 3; Junctional adhesion molecule C
Gene Aliases: 1110002N23Rik; JAM-2; JAM-3; JAM-C; JAM3; JAMC; Jcam3; UNQ859/PRO1868
UniProt ID: (Human) Q9BX67, (Mouse) Q9D8B7
Entrez Gene ID: (Human) 83700, (Mouse) 83964
angiogenesis
neutrophil homeostasis
adaptive immune response
myeloid progenitor cell differentiation
leukocyte migration involved in inflammatory response
cell-matrix adhesion
spermatid development
transmission of nerve impulse
establishment of cell polarity
extracellular matrix organization
axon regeneration
myelination
leukocyte migration
regulation of neutrophil chemotaxis
regulation of actin cytoskeleton organization by cell-cell adhesion
cell adhesion
spermatogenesis
cell migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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