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Immunogen sequence: HRPTCIVRTD SVKTPESEGN PLLE
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Jun dimerization protein 2; progesterone receptor co-activator
Gene Aliases: JDP2; JUNDM2
UniProt ID: (Human) Q8WYK2
Entrez Gene ID: (Human) 122953
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