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          • Primary Antibodies ›
          • JMJD5 Antibodies

          Invitrogen

          JMJD5 Polyclonal Antibody

          View all (14) JMJD5 antibodies

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          Cite JMJD5 Polyclonal Antibody

          • Antibody Testing Data (1)
          JMJD5 Antibody in Western Blot (WB)
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          JMJD5 Antibody in Western Blot (WB)
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          FIGURE: 1 / 1

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          JMJD5 Antibody (PA5-88168) in WB

          Western blot analysis of JMJD5 in extracts of various cell lines. Samples were incubated with JMJD5 Polyclonal antibody (Product # PA5-88168) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          JMJD5 Antibody in Western Blot (WB)

          Product Details

          PA5-88168

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 147-416 of human KDM8 (NP_0790492)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.05 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2804710

          Product Specific Information

          Immunogen sequence: THLPGKRPAR GSLPEQPCTK KARADHGLIP DVKLEKTVPR LHRPSLQHFR EQFLVPGRPV ILKGVADHWP CMQKWSLEYI QEIAGCRTVP VEVGSRYTDE EWSQTLMTVN EFISKYIVNE PRDVGYLAQH QLFDQIPELK QDISIPDYCS LGDGEEEEIT INAWFGPQGT ISPLHQDPQQ NFLVQVMGRK YIRLYSPQES GALYPHDTHL LHNTSQVDVE NPDLEKFPKF AKAPFLSCIL SPGEILFIPV KYWHYVRALD LSFSVSFWWS; Positive Samples: LO2, Mouse eye, Mouse liver; Cellular Location: Nucleus

          Target Information

          This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Bifunctional peptidase and arginyl-hydroxylase JMJD5; JmjC domain-containing protein 5; Jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8; lysine (K)-specific demethylase 8; Lysine-specific demethylase 8

          View more View less

          Gene Aliases: 3110005O21Rik; JMJD5; KDM8

          View more View less

          UniProt ID: (Human) Q8N371, (Mouse) Q9CXT6

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          Entrez Gene ID: (Human) 79831, (Mouse) 77035

          View more View less

          Function(s)
          chromatin binding metal ion binding histone demethylase activity (H3-K36 specific) oxidoreductase activity dioxygenase activity
          Process(es)
          G2/M transition of mitotic cell cycle transcription, DNA-templated regulation of transcription, DNA-templated cell cycle chromatin modification positive regulation of transcription, DNA-templated oxidation-reduction process histone H3-K36 demethylation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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