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Abnova
JRK Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
JRK Antibody (H00008629-B01P) in WB
Western Blot analysis of JRK expression in transfected 293T cell line (H00008629-T01) by JRK MaxPab polyclonal antibody.
Lane 1: JRK transfected lysate(62.48 KDa).
Lane 2: Non-transfected lysate.
Lane 1: JRK transfected lysate(62.48 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00008629-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
JRK (AAH43351.1, 1 a.a. approximately 568 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MASKPAAGKS RGEKRKRVVL TLKEKIDICT RLEKGESRKA LMQEYNVGMS TLYDIRAHKA QLLRFFASSD SNKALEQRRT LHTPKLEHLD RVLYEWFLGK RSEGVPVSGP MLIEKAKDFY EQMQLTEPCV FSGGWLWRFK ARHGIKKLDA SSEKQSADHQ AAEQFCAFFR SLAAEHGLSA EQVYNADETG LFWRCLPNPT PEGGAVPGPK QGKDRLTVLM CANATGSHRL KPLAIGKCSG PRAFKGIQHL PVAYKAQGNA WVDKEIFSDW FHHIFVPSVR EHFRTIGLPE DSKAVLLLDS SRAHPQEAEL VSSNVFTIFL PASVASLVQP MEQGIRRDFM RNFINPPVPL QGPHARYNMN DAIFSVACAW NAVPSHVFRR AWRKLWPSVA FAEGSSSEEE LEAECFPVKP HNKSFAHILE LVKEGSSCPG QLRQRQAASW GVAGREAEGG RPPAATSPAE VVWSSEKTPK ADQDGRGDPG EGEEVAWEQA AVAFDAVLRF AERQPCFSAQ EVGQLRALRA VFRSQQQVRR RRGALGAVVK VEALQEGPGG CGATAQSPLP CSSTAGDN
Target Information
The JRK gene encodes a protein known as JRK (Jerky) homolog, which is implicated in various cellular processes, including DNA damage response and transcription regulation. JRK is conserved across multiple species and plays a role in the stability of neuronal functions and development. It is notably associated with neuropsychiatric disorders, where aberrations in its expression or function can contribute to conditions such as epilepsy and intellectual disabilities. The protein interacts with other cellular components to influence gene expression patterns, which are critical for maintaining normal neuronal activity. JRK is also studied for its potential involvement in cancer biology, where it may impact cell cycle regulation and genomic stability. Understanding the functions and mechanisms of JRK can provide insights into its roles in both normal physiological processes and disease states, particularly in the context of the nervous system and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: jerky homolog; Jerky protein homolog; Jrk homolog
Gene Aliases: jerky; JH8; JRK
UniProt ID: (Human) O75564
Entrez Gene ID: (Human) 8629
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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