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Invitrogen
JRK Polyclonal Antibody
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FIGURE: 1 / 1
JRK Antibody (PA5-98370) in WB
Western Blot analysis of JRK using a JRK Polyclonal antibody (Product # PA5-98370). Positive WB detected in: SH-SY5Y whole cell lysate, Mouse heart tissue. All lanes: JRK antibody at 1:1000. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 62 kDa.
Product Details
PA5-98370
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence from Human Jerky protein homolog protein (465-483AA)
Conjugate
Form
Liquid
Concentration
2.23 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2812983
Target Information
The JRK gene encodes a protein known as JRK (Jerky) homolog, which is implicated in various cellular processes, including DNA damage response and transcription regulation. JRK is conserved across multiple species and plays a role in the stability of neuronal functions and development. It is notably associated with neuropsychiatric disorders, where aberrations in its expression or function can contribute to conditions such as epilepsy and intellectual disabilities. The protein interacts with other cellular components to influence gene expression patterns, which are critical for maintaining normal neuronal activity. JRK is also studied for its potential involvement in cancer biology, where it may impact cell cycle regulation and genomic stability. Understanding the functions and mechanisms of JRK can provide insights into its roles in both normal physiological processes and disease states, particularly in the context of the nervous system and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: jerky homolog; Jerky protein; Jerky protein homolog; Jrk homolog
Gene Aliases: jerky; JH8; JRK
UniProt ID: (Human) O75564, (Mouse) Q60976
Entrez Gene ID: (Human) 8629, (Mouse) 16469
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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