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JUNB Polyclonal Antibody

JUNB Antibody in Immunocytochemistry (ICC/IF)

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JUNB Antibody (10486-1-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells using 10486-1-AP (JUNB antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

JUNB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

JUNB Antibody in Immunoprecipitation (IP)

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Product Details

10486-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

JUNB Fusion Protein Ag0752 (1-200 aa encoded by BC004250)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MCTKMEQPF YHDDSYTATG YGRAPGGLSL HDYKLLKPSL AVNLADPYRS LKAPGARGPG PEGGGGGSYF SGQGSDTGAS LKLASSELER LIVPNSNGVI TTTPTPPGQY FYPRGGGSGG GAGGAGGGVT EEQEGFADGF VKALDDLHKM NHVTPPNVSL GATGGPPAGP GGVYAGPEPP PVYTNLSSYS PASASSGGAG A (1-200 aa encoded by BC004250)

Target Information

JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1.

Experimental cell research

Hu X,Li M,Zhang Y,Sang K,Zhang Y,Li W,Liu B,Wan L,Du B,Qian J,Meng F,Fu Y,Dai M,Gao G,Ye H

Wed Mar 01 00:00:00 UTC 2023

Identification of key modules and candidate genes associated with endometriosis based on transcriptome data via bioinformatics analysis.

Pathology, research and practice

Zheng W,Xiang D,Wen D,Luo M,Liang X,Cao L

Sat Apr 01 00:00:00 UTC 2023

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.

Pharmacological research

Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S

Wed Jun 01 00:00:00 UTC 2022

Systematic Survey of the Regulatory Networks of the Long Noncoding RNA BANCR in Cervical Cancer Cells.

Journal of proteome research

Wang B,Wang M,Jia S,Li T,Yang M,Ge F

Fri Apr 01 00:00:00 UTC 2022

Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma.

American journal of cancer research

Zhao WS,Yan WP,Chen DB,Dai L,Yang YB,Kang XZ,Fu H,Chen P,Deng KJ,Wang XY,Xie XW,Chen HS,Chen KN

Wed Sep 30 00:00:00 UTC 2020

USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.

The Journal of experimental medicine

Chen S,Yun F,Yao Y,Cao M,Zhang Y,Wang J,Song X,Qian Y

Mon Nov 05 00:00:00 UTC 2018

USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.

The Journal of experimental medicine

Chen S,Yun F,Yao Y,Cao M,Zhang Y,Wang J,Song X,Qian Y

Mon Nov 05 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB

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Gene Aliases: AP-1; Jun-b; JUNB

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UniProt ID: (Human) P17275, (Rat) P24898, (Mouse) P09450

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Entrez Gene ID: (Human) 3726, (Rat) 24517, (Mouse) 16477

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription coactivator activity transcription corepressor activity protein binding transcription factor binding RNA polymerase II regulatory region sequence-specific DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding protein heterodimerization activity

Process(es)

vasculogenesis osteoblast differentiation in utero embryonic development trophectodermal cell differentiation regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter female pregnancy response to light stimulus response to mechanical stimulus cellular process response to organic cyclic compound osteoclast differentiation response to progesterone cellular response to hormone stimulus osteoblast proliferation response to cytokine response to drug response to peptide hormone positive regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter decidualization response to corticosterone response to cAMP regulation of cell cycle embryonic process involved in female pregnancy labyrinthine layer blood vessel development cellular response to calcium ion negative regulation of transcription from RNA polymerase II promoter response to radiation regulation of cell death response to lipopolysaccharide regulation of cell proliferation transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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JUNB Polyclonal Antibody

JUNB Antibody (10486-1-AP) in ICC/IF

Product Details

10486-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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