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Product Details
BS-9706R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human JWA.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
JWA protein expression is affected by vitamin A and may be associated with the cytoskeleton. A protein similar to JWA in rats may play a role in the regulation of cell differentiation by inhibiting the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Addicsin; ADP-ribosylation factor GTPase 6 interacting protein 5; ADP-ribosylation factor like GTPase 6 interacting protein 5; ADP-ribosylation factor-like 6 interacting protein 5; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; aip-5; ARL-6-interacting protein 5; cytoskeleton related vitamin A responsive protein; Cytoskeleton-related vitamin A-responsive protein; dermal papilla derived protein 11; Dermal papilla-derived protein 11; glutamate transporter EAAC1 interacting protein; Glutamate transporter EAAC1-interacting protein; glutamate transporter EEAC1-associated protein; GTRAP3-18; JM5; PRA1 domain family 3; PRA1 family protein 3; Prenylated Rab acceptor protein 2; Protein JWa; putative MAPK activating protein PM27; Putative MAPK-activating protein PM27
Gene Aliases: 5930404D22Rik; addicsin; addiscin; Aip-5; Aip5; ARL6IP5; AV001879; DERP11; GTRAP3-18; hp22; HSPC127; jmx; JWA; PRA2; PRAF3; Yip6b
UniProt ID: (Human) O75915, (Mouse) Q8R5J9, (Rat) Q9ES40
Entrez Gene ID: (Human) 10550, (Mouse) 65106, (Rat) 66028
intrinsic apoptotic signaling pathway in response to oxidative stress
negative regulation of mitochondrial membrane potential
L-glutamate transport
positive regulation of stress-activated MAPK cascade
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transport
negative regulation of L-glutamate transport
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