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Invitrogen
JWA Polyclonal Antibody
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JWA Antibody (PA5-109412) in WB
Western blot analysis of JWA in extracts of Mouse thymus. Samples were incubated with JWA Polyclonal antibody (Product # PA5-109412) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-109412
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human ARL6IP5 (NP_006398.1).
Conjugate
Form
Liquid
Concentration
1.07 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854823
Product Specific Information
Immunogen sequence: TFVMVVMLAS YFLISMFGGV MVFVFGITFP LLLMFIHASL RLRNLKNKLE NKMEGIGLKR TPMGIVLDAL EQQEEGINRL TDYISKVKE
Target Information
JWA protein expression is affected by vitamin A and may be associated with the cytoskeleton. A protein similar to JWA in rats may play a role in the regulation of cell differentiation by inhibiting the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Addicsin; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; ARL-6-interacting protein 5; Glutamate transporter EAAC1-interacting protein; GTRAP3-18; PRA1 family protein 3; Prenylated Rab acceptor protein 2; Protein JWa
Gene Aliases: 5930404D22Rik; addiscin; Aip-5; Aip5; Arl6ip5; AV001879; Gtrap3-18; Jwa; Pra2; Praf3
UniProt ID: (Mouse) Q8R5J9
Entrez Gene ID: (Mouse) 65106
intrinsic apoptotic signaling pathway in response to oxidative stress
negative regulation of mitochondrial membrane potential
L-glutamate transport
positive regulation of stress-activated MAPK cascade
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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