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Invitrogen
Jagged2 Monoclonal Antibody (K.902.6)
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Product Details
MA5-14979
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
K.902.6
Immunogen
Synthetic peptide corresponding to residues surrounding Pro1212 of human Jagged2
Conjugate
Form
Liquid
Concentration
50 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10984753
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with Jagged1.
Target Information
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Jagged2; Protein jagged-2
Gene Aliases: HJ2; JAG2; SER2
UniProt ID: (Human) Q9Y219
Entrez Gene ID: (Human) 3714
skeletal system development
in utero embryonic development
respiratory system process
cell cycle
Notch signaling pathway
Notch receptor processing
spermatogenesis
auditory receptor cell fate commitment
morphogenesis of embryonic epithelium
cell differentiation
regulation of cell adhesion
T cell differentiation
regulation of cell migration
regulation of cell proliferation
odontogenesis of dentin-containing tooth
gamma-delta T cell differentiation
thymic T cell selection
positive regulation of Notch signaling pathway
epithelial cell apoptotic process involved in palatal shelf morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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