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Invitrogen
JunB Recombinant Rabbit Monoclonal Antibody (15H19L4)
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FIGURE: 1 / 4
JunB Antibody (701702) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized HeLa cells for detection of JUNB using Anti-JUNB Recombinant Rabbit Monoclonal Antibody (Product # 701702, 1-2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of JUNB protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). Panel c) r... View More
Product Details
701702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
15H19L4
Immunogen
Peptides corresponding to Human JUNB (aa 6-25, 262-279)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2609325
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Mouse and Feline.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; Transcription factor JunB
Gene Aliases: AP-1; JUNB
UniProt ID: (Human) P17275
Entrez Gene ID: (Human) 3726
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
osteoblast differentiation
trophectodermal cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to light stimulus
response to mechanical stimulus
regulation of cell death
osteoclast differentiation
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
osteoblast proliferation
response to cytokine
regulation of cell proliferation
response to drug
response to peptide hormone
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
decidualization
response to corticosterone
response to cAMP
regulation of cell cycle
embryonic process involved in female pregnancy
labyrinthine layer blood vessel development
cellular response to calcium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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