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Invitrogen
JunD Polyclonal Antibody
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Product Details
PA5-142263
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence CQLLPQHQVPAY (aa 336-347).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2932916
Product Specific Information
Additional Information: This antibody is expected NOT to cross-react with Jun oncogen (NP_002219.1, GeneID 3725).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AP1; JUN D; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Oncogene Jun-D; Transcription factor AP-1 subunit JunD; transcription factor jun-D; Transcription factor JunD
Gene Aliases: Jun-d; Jund; Jund1
UniProt ID: (Mouse) P15066
Entrez Gene ID: (Mouse) 16478
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
ligand-dependent nuclear receptor binding
enzyme binding
sequence-specific DNA binding
transcription regulatory region DNA binding
negative regulation of transcription from RNA polymerase II promoter
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to mechanical stimulus
regulation of cell death
response to lipopolysaccharide
cellular response to hormone stimulus
response to cytokine
regulation of cell proliferation
response to drug
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
response to cAMP
regulation of cell cycle
cellular response to calcium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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