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Invitrogen
JunD Polyclonal Antibody
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Product Details
PA5-27624
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human JunD. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545100
Product Specific Information
Recommended positive controls: 293T, Raji.
Predicted reactivity: Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; AP1; JUN D; jun D proto-oncogene; JunD-FL isoform; Oncogene Jun-D; Transcription factor AP-1 subunit JunD; Transcription factor JunD
Gene Aliases: AP-1; JUND
UniProt ID: (Human) P17535
Entrez Gene ID: (Human) 3727
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
ligand-dependent nuclear receptor binding
enzyme binding
transcription regulatory region DNA binding
negative regulation of transcription from RNA polymerase II promoter
osteoblast development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
aging
circadian rhythm
response to radiation
response to light stimulus
response to mechanical stimulus
regulation of cell death
response to lipopolysaccharide
cellular response to hormone stimulus
response to cytokine
regulation of cell proliferation
response to drug
response to peptide hormone
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
response to cAMP
regulation of cell cycle
cellular response to calcium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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