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Invitrogen
KANK3 Polyclonal Antibody
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Product Details
PA5-62333
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KANK3. Recombinant protein control fragment (Product #RP-99982).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642869
Product Specific Information
Immunogen sequence: QLREATTQTP WSCAEKAAQT ESPAEAPSLT QESSPGSMDG DRAVAPAGIL KSIMK
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 51%.
Target Information
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat domain 47; Ankyrin repeat domain-containing protein 47; kidney ankyrin repeat-containing protein 3; KN motif and ankyrin repeat domain-containing protein 3
Gene Aliases: ANKRD47; KANK3
UniProt ID: (Human) Q6NY19
Entrez Gene ID: (Human) 256949
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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