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FIGURE: 1 / 4
Sequence of this protein is as follows: MSLLMISENV KLAREYALLG NYDSAMVYYQ GVLDQMNKYL YSVKDTYLQQ KWQQVWQEIN VEAKHVKDIM KTLESFKLDS TPLKAAQHDL PASEGEVWSM PVPVERRPSP GPRKRQSSQY SDPKSHGNRP STTVRVHRSS AQNVHNDRGK AVRCREKKEQ NKGREEKGVL MVGPPGTGKT LLAKAVATEC KTTFFNVSSS TLTSKYRGES EKLVRLLFEM ARFYSPATIF IDEIDSICSR RGTSEEHEAS RRVKAELLVQ MDGVGGTSEN DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSGMR P
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: katanin p60 (ATPase containing) subunit A 1; katanin p60 (ATPase-containing) subunit A 1; Katanin p60 ATPase-containing subunit A1; katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}; katanin p60 subunit A 1; Katanin p60 subunit A1; katanin p60 subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}; KATNA1; lipotransin; microtubule severing protein; p60 katanin; p60 katanin {ECO:0000255|HAMAP-Rule:MF_03023}
Gene Aliases: KATNA1
UniProt ID: (Human) O75449, (Rat) Q6E0V2
Entrez Gene ID: (Human) 11104, (Rat) 292464, (Mouse) 23924
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