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Invitrogen
KBTBD3 Polyclonal Antibody
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Product Details
PA5-61495
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KBTBD3. Recombinant protein control fragment (Product #RP-97514).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642893
Product Specific Information
Immunogen sequence: IMDAIKCVQG SGGLFPDARP STTEKYIFIH KTEENGENQY TFCYNIKSDS WKILPQSHLI DLPGSSLSSY GEKIFLTGGC KGKCCRTVRL HIAESYHDAT DQTWCY
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; kelch repeat and BTB (POZ) domain containing 3; Kelch repeat and BTB domain-containing protein 3
Gene Aliases: BKLHD3; KBTBD3
UniProt ID: (Human) Q8NAB2
Entrez Gene ID: (Human) 143879
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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