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Invitrogen
KCNH3 Polyclonal Antibody
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FIGURE: 1 / 5
KCNH3 Antibody (PA5-106705) in IHC (P)
Immunohistochemistry analysis of KCNH3 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KCNH3 polyclonal antibody (Product # PA5-106705) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106705
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNH3(Accession Q9ULD8), corresponding to amino acid residues P1015-I1065.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854373
Product Specific Information
Antibody detects endogenous levels of total KCNH3.
Target Information
The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BEC1; Brain-specific eag-like channel 1; ELK channel 2; ether a go-go like; ether-a-go-go K(+) channel family member; Ether-a-go-go-like potassium channel 2; potassium channel, voltage gated eag related subfamily H, member 3; Potassium voltage-gated channel subfamily H member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; rElk2; Voltage-gated inwardly rectifying potassium channel KCNH3; Voltage-gated potassium channel subunit Kv12.2
Gene Aliases: AU019351; BEC1; C030044P22Rik; ELK2; KCNH3; KIAA1282; Kv12.2; Melk2
UniProt ID: (Human) Q9ULD8, (Rat) O89047, (Mouse) Q9WVJ0
Entrez Gene ID: (Human) 23416, (Rat) 27150, (Mouse) 16512
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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