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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: KCNH4.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BEC2; Brain-specific eag-like channel 2; ELK channel 1; ether-a-go-go K(+) channel family member; Ether-a-go-go-like potassium channel 1; potassium channel, voltage gated eag related subfamily H, member 4; Potassium voltage-gated channel subfamily H member 4; potassium voltage-gated channel, subfamily H (eag-related), member 4; rElk1; Voltage-gated delayed rectifier potassium channel KCNH4; Voltage-gated potassium channel subunit Kv12.3
Gene Aliases: BEC2; ELK1; Elk3; KCNH4; Kv12.3
UniProt ID: (Human) Q9UQ05, (Rat) Q9R1T9
Entrez Gene ID: (Human) 23415, (Mouse) 380728, (Rat) 114032
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