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The antibody detects endogenous levels of total KCNK13 protein.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: K2P13.1 potassium channel; Potassium channel subfamily K member 13; potassium channel, subfamily K, member 13; potassium channel, two pore domain subfamily K, member 13; Tandem pore domain halothane-inhibited potassium channel 1; tandem pore domain potassium channel THIK-1; THIK-1
Gene Aliases: BB085247; F730021E22Rik; Gm1570; Gm1685; K2p13.1; KCNK13; THIK-1; THIK1
UniProt ID: (Human) Q9HB14, (Mouse) Q8R1P5
Entrez Gene ID: (Human) 56659, (Mouse) 217826
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