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Proteintech
KCNMB4 Monoclonal Antibody (4H7G3)
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Product Details
60122-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4H7G3
Immunogen
KCNMB4 Fusion Protein Ag5618 (46-176 aa encoded by BC042446)
Conjugate
Form
Liquid
Concentration
0.83 mg/mL
Purification
Caprylic acid precipitation
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DLQATEANC TVLSVQQIGE VFECTFTCGA DCRGTSQYPC VQVYVNNSES NSRALLHSDE HQLLTNPKCS YIPPCKRENQ KNLESVMNWQ QYWKDEIGSQ PFTCYFNQHQ RPDDVLLHRT HDEIVLLHCF LW (46-176 aa encoded by BC042446)
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: big potassium channel beta subunit 4; BK channel beta subunit 4; BK channel subunit beta-4; BKbeta4; Calcium-activated potassium channel subunit beta-4; Calcium-activated potassium channel, subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; hbeta4; K(VCA)beta-4; KCMB4; large conductance calcium-dependent potassium ion channel beta 4 subunit; Maxi K channel subunit beta-4; MaxiK channel beta-subunit 4; potassium channel subfamily M regulatory beta subunit 4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; Slo-beta-4; Slowpoke beta 4
Gene Aliases: 1700058G18Rik; 2900045G12Rik; KCNMB4
UniProt ID: (Human) Q86W47, (Mouse) Q9JIN6
Entrez Gene ID: (Human) 27345, (Mouse) 58802
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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