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Proteintech
KCNN4 Monoclonal Antibody (2A6G5)
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Product Details
60276-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2A6G5
Immunogen
KCNN4 Fusion Protein Ag19774 (128-427 aa encoded by BC015337)
Conjugate
Form
Liquid
Concentration
1.05 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VQDLGAPLT SPQPWPGFLG QGEALLSLAM LLRLYLVPRA VLLRSGVLLN ASYRSIGALN QVRFRHWFVA KLYMNTHPGR LLLGLTLGLW LTTAWVLSVA ERQAVNATGH LSDTLWLIPI TFLTIGYGDV VPGTMWGKIV CLCTGVMGVC CTALLVAVVA RKLEFNKAEK HVHNFMMDIQ YTKEMKESAA RVLQEAWMFY KHTRRKESHA ARRHQRKLLA AINAFRQVRL KHRKLREQVN SMVDISKMHM ILYDLQQNLS SSHRALEKQI DTLAGKLDAL TELLSTALGP RQLPEPSQQS K (128-427 aa encoded by BC015337)
Target Information
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Gardos channel; HIK1; hKCa4; IK1; IKCa; IKCa1; Intermediate conductance calcium-activated potassium channel protein 4; intermediate conductance K channel; intermediate-conductance Ca-activated K channel; KCa3.1; KCa4; KCNN 4; mIK1; mKCa4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; Putative Gardos channel; SK4; SKCa 4; SKCa4; small conductance calcium-activated potassium channel 4
Gene Aliases: DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; KCNN4; mIKCa1; rKCNN4c; rSK4; SK4; SKCas
UniProt ID: (Human) O15554, (Mouse) O89109
Entrez Gene ID: (Human) 3783, (Rat) 65206, (Mouse) 16534
immune system process
potassium ion transport
calcium ion transport
anion transport
cell volume homeostasis
stabilization of membrane potential
phospholipid translocation
saliva secretion
positive regulation of protein secretion
positive regulation of T cell receptor signaling pathway
potassium ion export
potassium ion transmembrane transport
defense response
transport
ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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